A human neutrophil interacting with Klebsiella pneumoniae (pink), a multidrug-resistant bacterium. Credit: NIAID.

I would like to sound one note of warning. Penicillin is to all intents and purposes non-poisonous so there is no need to worry about giving an overdose and poisoning the patient. There may be a danger, though, in underdosage. It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body

The scientist who discovered penicillin used his Nobel speech to warn us of antibiotic resistance.
↩︎ Nobel Prize
Feb 7, 2017

The scale of the superbug problem is massive.

Ten million people could die per year by 2050 from antibiotic-resistant diseases. That’s about how many people die from heart attack every year now. And a lot of therapies like chemo and transplants may become more dangerous because they expose the body to a higher rate of infection

There will be nothing exceptional about superbugs. They will be normal, and they'll drive up meat prices, kill our forests, and make childbirth more dangerous.

Feb 7, 2017

Convenience, laziness, perverse financial incentives and sheer bad luck have conspired to nullify almost every attempt to stop the emergence of resistance.

We never came up with a system to correct the dangerous misalignment between those who misuse drugs and those who pay the cost.
↩︎ Economist
Feb 7, 2017

Antibiotics don't have to be ingested to cause bacteria to evolve. As this mini doc shows, the water near Hyderabad, India is so saturated with antibiotics from a pharmaceutical facility, it causes deathly infections to bloom. 

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